Publications
McDonald NA, Tao L, Dong M-Q, Shen K. (2023) SAD-1 kinase controls presynaptic phase separation by relieving SYD-2/Liprin-α autoinhibition. PLoS Biology. 21(12): e3002421.
McDonald NA, Shen K. (2021) Finding functions of phase separation in the presynapse. Current Opinion in Neurobiology. 69:178-184.
McDonald NA, Fetter RD, Shen K. (2020) Assembly of synaptic active zones requires phase separation of scaffold molecules. Nature. 588(7838):454-458.
McDonald NA, Shen K. (2021) Finding functions of phase separation in the presynapse. Current Opinion in Neurobiology. 69:178-184.
McDonald NA, Fetter RD, Shen K. (2020) Assembly of synaptic active zones requires phase separation of scaffold molecules. Nature. 588(7838):454-458.
Snider CE, Chandra M, McDonald NA, Willet AH, Collier SE, Ohi MD, Jackson LP, Gould KL. (2020) Opposite Surfaces of the Cdc15 F-BAR Domain Create a Membrane Platform That Coordinates Cytoskeletal and Signaling Components for Cytokinesis. Cell Reports. 33(12):108526.
Bhattacharjee R*, Mangione MC*, Wos M, Chen JS, Snider CE, Roberts-Galbraith RH, McDonald NA, Presti LL, Martin SG, Gould KL. DYRK kinase Pom1 drives F-BAR protein Cdc15 from the membrane to promote medial division. Molecular Biology of the Cell. 31(9):917-929.
Liu Y*, McDonald NA*, Naegele SM, Gould KL, Wu JQ. (2019) The F-BAR Domain of Rga7 Relies on a Cooperative Mechanism of Membrane Binding with a Partner Protein during Fission Yeast Cytokinesis. Cell Reports. 26(10):2540-2548.e4.
McDonald NA, Lind AL, Smith SE, Li R, Gould KL. (2017) Nanoscale architecture of the Schizosaccharomyces pombe contractile ring. Elife. e28865.
Pyburn TM, Foegeding NJ, González-Rivera C, McDonald NA, Gould KL, Cover TL, Ohi MD. (2016) Structural organization of membrane-inserted hexamers formed by Helicobacter pylori VacA toxin. Molecular Microbiology. 102(1):22-36.
McDonald NA, Gould KL. (2016) Linking up at the BAR: Oligomerization and F-BAR protein function. Cell Cycle. 15(15):1977-85.
McDonald NA, Takizawa Y, Feoktistova A, Xu P, Ohi MD, Vander Kooi CW, Gould KL. (2016) The Tubulation Activity of a Fission Yeast F-BAR Protein Is Dispensable for Its Function in Cytokinesis. Cell Reports. 26;14(3):534-546.
McDonald NA, Gould KL. (2016) Characterization of Cytokinetic F-BARs and Other Membrane-Binding Proteins. Methods in Molecular Biology. 1369:181-9.
McDonald NA, Vander Kooi CW, Ohi MD, Gould KL. (2015) Oligomerization but Not Membrane Bending Underlies the Function of Certain F-BAR Proteins in Cell Motility and Cytokinesis. Developmental Cell. 2015 Dec 21;35(6):725-36.
Willet AH*, McDonald NA*, Gould KL. (2015) Regulation of contractile ring formation and septation in Schizosaccharomyces pombe. Current Opinion in Microbiology. 28:46-52.
Willet AH, McDonald NA, Bohnert KA, Baird MA, Allen JR, Davidson MW, Gould KL. (2015) The F-BAR Cdc15 promotes contractile ring formation through the direct recruitment of the formin Cdc12. The Journal of Cell Biology. 208(4):391-9.
Ren L, Willet AH, Roberts-Galbraith RH, McDonald NA, Feoktistova A, Chen JS, Huang H, Guillen R, Boone C, Sidhu SS, Beckley JR, Gould KL. (2015) The Cdc15 and Imp2 SH3 domains cooperatively scaffold a network of proteins that redundantly ensure efficient cell division in fission yeast. Molecular Biology of the Cell. 26(2):256-69.
Chen JS, Beckley JR, McDonald NA, Ren L, Mangione M, Jang SJ, Elmore ZC, Rachfall N, Feoktistova A, Jones CM, Willet AH, Guillen R, Bitton DA, Bähler J, Jensen MA, Rhind N, Gould KL. (2014) Identification of new players in cell division, DNA damage response, and morphogenesis through construction of Schizosaccharomyces pombe deletion strains. G3. 5(3):361-70.
Weßling R*, Epple P*, Altmann S*, He Y*, Yang L*, Henz SR, McDonald N, Wiley K, Bader KC, Gläßer C, Mukhtar MS, Haigis S, Ghamsari L, Stephens AE, Ecker JR, Vidal M, Jones JD, Mayer KF, Ver Loren van Themaat E, Weigel D, Schulze-Lefert P, Dangl JL, Panstruga R, Braun P. (2014) Convergent targeting of a common host protein-network by pathogen effectors from three kingdoms of life. Cell Host & Microbe. 16(3):364-75.
Mukhtar MS*, Carvunis AR*, Dreze M*, Epple P*, Steinbrenner J, Moore J, Tasan M, Galli M, Hao T, Nishimura MT, Pevzner SJ, Donovan SE, Ghamsari L, Santhanam B, Romero V, Poulin MM, Gebreab F, Gutierrez BJ, Tam S, Monachello D, Boxem M, Harbort CJ, McDonald N, Gai L, Chen H, He Y, Vandenhaute J, Roth FP, Hill DE, Ecker JR, Vidal M, Beynon J, Braun P, Dangl JL. (2011) Independently evolved virulence effectors converge onto hubs in a plant immune system network. Science. 333(6042):596-601.
Bhattacharjee R*, Mangione MC*, Wos M, Chen JS, Snider CE, Roberts-Galbraith RH, McDonald NA, Presti LL, Martin SG, Gould KL. DYRK kinase Pom1 drives F-BAR protein Cdc15 from the membrane to promote medial division. Molecular Biology of the Cell. 31(9):917-929.
Liu Y*, McDonald NA*, Naegele SM, Gould KL, Wu JQ. (2019) The F-BAR Domain of Rga7 Relies on a Cooperative Mechanism of Membrane Binding with a Partner Protein during Fission Yeast Cytokinesis. Cell Reports. 26(10):2540-2548.e4.
McDonald NA, Lind AL, Smith SE, Li R, Gould KL. (2017) Nanoscale architecture of the Schizosaccharomyces pombe contractile ring. Elife. e28865.
Pyburn TM, Foegeding NJ, González-Rivera C, McDonald NA, Gould KL, Cover TL, Ohi MD. (2016) Structural organization of membrane-inserted hexamers formed by Helicobacter pylori VacA toxin. Molecular Microbiology. 102(1):22-36.
McDonald NA, Gould KL. (2016) Linking up at the BAR: Oligomerization and F-BAR protein function. Cell Cycle. 15(15):1977-85.
McDonald NA, Takizawa Y, Feoktistova A, Xu P, Ohi MD, Vander Kooi CW, Gould KL. (2016) The Tubulation Activity of a Fission Yeast F-BAR Protein Is Dispensable for Its Function in Cytokinesis. Cell Reports. 26;14(3):534-546.
McDonald NA, Gould KL. (2016) Characterization of Cytokinetic F-BARs and Other Membrane-Binding Proteins. Methods in Molecular Biology. 1369:181-9.
McDonald NA, Vander Kooi CW, Ohi MD, Gould KL. (2015) Oligomerization but Not Membrane Bending Underlies the Function of Certain F-BAR Proteins in Cell Motility and Cytokinesis. Developmental Cell. 2015 Dec 21;35(6):725-36.
Willet AH*, McDonald NA*, Gould KL. (2015) Regulation of contractile ring formation and septation in Schizosaccharomyces pombe. Current Opinion in Microbiology. 28:46-52.
Willet AH, McDonald NA, Bohnert KA, Baird MA, Allen JR, Davidson MW, Gould KL. (2015) The F-BAR Cdc15 promotes contractile ring formation through the direct recruitment of the formin Cdc12. The Journal of Cell Biology. 208(4):391-9.
Ren L, Willet AH, Roberts-Galbraith RH, McDonald NA, Feoktistova A, Chen JS, Huang H, Guillen R, Boone C, Sidhu SS, Beckley JR, Gould KL. (2015) The Cdc15 and Imp2 SH3 domains cooperatively scaffold a network of proteins that redundantly ensure efficient cell division in fission yeast. Molecular Biology of the Cell. 26(2):256-69.
Chen JS, Beckley JR, McDonald NA, Ren L, Mangione M, Jang SJ, Elmore ZC, Rachfall N, Feoktistova A, Jones CM, Willet AH, Guillen R, Bitton DA, Bähler J, Jensen MA, Rhind N, Gould KL. (2014) Identification of new players in cell division, DNA damage response, and morphogenesis through construction of Schizosaccharomyces pombe deletion strains. G3. 5(3):361-70.
Weßling R*, Epple P*, Altmann S*, He Y*, Yang L*, Henz SR, McDonald N, Wiley K, Bader KC, Gläßer C, Mukhtar MS, Haigis S, Ghamsari L, Stephens AE, Ecker JR, Vidal M, Jones JD, Mayer KF, Ver Loren van Themaat E, Weigel D, Schulze-Lefert P, Dangl JL, Panstruga R, Braun P. (2014) Convergent targeting of a common host protein-network by pathogen effectors from three kingdoms of life. Cell Host & Microbe. 16(3):364-75.
Mukhtar MS*, Carvunis AR*, Dreze M*, Epple P*, Steinbrenner J, Moore J, Tasan M, Galli M, Hao T, Nishimura MT, Pevzner SJ, Donovan SE, Ghamsari L, Santhanam B, Romero V, Poulin MM, Gebreab F, Gutierrez BJ, Tam S, Monachello D, Boxem M, Harbort CJ, McDonald N, Gai L, Chen H, He Y, Vandenhaute J, Roth FP, Hill DE, Ecker JR, Vidal M, Beynon J, Braun P, Dangl JL. (2011) Independently evolved virulence effectors converge onto hubs in a plant immune system network. Science. 333(6042):596-601.